5 Bible Verses about Alexander The Great

After this I kept looking, and behold, another one (the Greek Empire of Alexander the Great), like a leopard, which had on its back four wings like those of a bird; the beast also had four heads (Alexander’s generals, his successors), and power to rule was given to it.

As I was observing [this], behold, a male goat (Greece) was coming from the west [rushing] across the face of the whole earth without touching the ground; and the goat had a conspicuous and remarkable horn (Alexander the Great) between his eyes. He came up to the ram that had the two horns, which I had seen standing in front of the canal, and charged at him in [the fury of] his power and wrath. [In my vision] I saw him come close to the ram (Medo-Persia), and he was filled with rage toward him; and the goat (Greece) struck the ram and shattered his two horns, and the ram had no strength to stand before him. So the goat threw him to the ground and trampled on him, and there was no one who could rescue the ram from his power. read more.
Then the male goat magnified himself exceedingly, and when he was [young and] strong, the great horn (Alexander) was [suddenly] broken; and in its place there came up four prominent horns [among whom the kingdom was divided, one] toward [each of] the four winds of heaven. Out of one of them (Antiochus IV Epiphanes) came forth a rather small horn [but one of irreverent presumption and profane pride] which grew exceedingly powerful toward the south, toward the east, and toward the Beautiful Land (Israel).

Then a mighty [warlike, threatening] king will arise who will rule with great authority and do as he pleases.

The oracle (a burdensome message) of the word of the Lord is against the land of Hadrach [in Syria], with Damascus as its resting place (for the eyes of men, especially of all the tribes of Israel, are toward the Lord),
And Hamath also, which borders on it (Damascus),
Tyre and Sidon, though they are very wise.

For Tyre built herself an [impregnable] stronghold [on an island offshore],
And she has heaped up silver like dust
And gold like the mire of the streets.
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Behold, the Lord will dispossess her
And throw her wealth into the sea;
And Tyre will be devoured by fire.

Ashkelon will see it and fear;
Gaza will writhe in pain,
And Ekron, for her hope and expectation, has been ruined.
The king will perish from Gaza,
And Ashkelon will not be inhabited.

And a mongrel race will live in Ashdod,
And I will put an end to the pride and arrogance of the Philistines.

I will take the blood from their mouths
And their detestable things from between their teeth [those repulsive, idolatrous sacrifices eaten with the blood].
Then they too will be a remnant for our God,
And be like a clan in Judah,
And Ekron will be like one of the Jebusites.

Then I will camp around My house [as a guard] because of an army,
Because of him who passes by and returns;
And no oppressor will again overrun them (Israel),
For now My eyes are upon them [providentially protecting them].

The shaggy (rough-coated) male goat represents the kingdom of Greece, and the great horn between his eyes is the first king.