7 Bible Verses about Despondency, Causes Of

So Jacob tore his clothes, dressed himself in sackcloth, and then mourned many days for his son. All his sons and daughters showed up to comfort him, but he refused to be comforted. He kept saying, "Leave me alone! I'll go down to the next world, still mourning for my son." So Joseph's father wept for him.

A composition by King Hezekiah of Judah, following his illness and recovery: I said, "Must I leave in the prime of my life? Must I be consigned to the control of Sheol? Bitter are my years!" I said, "I won't see the LORD in the land of the living; and I'll no longer observe human beings among the denizens of the grave.read more.
My house has been plucked up and vanishes from me like a shepherd's tent; like a weaver, I've taken account of my life, and he cuts me off from the loom day and night you make an end of me.

So forgive and comfort him, or else he will drown in his excessive grief.

On the first day Amminadab's son Nahshon, from the tribe of Judah, presented as his offering a silver dish weighing 130 shekels and a silver bowl weighing 70 shekels (calculated according to the shekel of the sanctuary), both filled with choice flour mixed with oil for a grain offering;

For even when we came to Macedonia, our bodies had no rest. We suffered in a number of ways. Outwardly there were conflicts, inwardly there were fears. Yet God, who comforts those who feel miserable, comforted us by the arrival of Titus,

Deeply shaken, the king went up to the chamber overlooking the city gate, weeping bitterly and crying out as he went along, "My son Absalom! My son! My son Absalom! I wish I had died instead of you, Absalom my son, my son!"

In the morning you'll say, "I wish it were evening.' Yet in the evening you'll say, "I wish it were morning,' on account of what you'll dread and what you'll see.