'Estranged' in the Bible

He hath put my brethren far from me, and mine acquaintance are quite estranged from me.

because they have forsaken me, and have estranged this place from me, and have burned incense in it unto other gods, whom neither they nor their fathers have known, nor the kings of Judah; and have filled this place with the blood of innocents;

that I may take the house of Israel by their own heart, because they are all estranged from me through their idols.

being darkened in understanding, estranged from the life of God by reason of the ignorance which is in them, by reason of the hardness of their hearts,