Revelation 9:18-21

One-third of mankind was killed by these three plagues: the fire, smoke, and sulphur that kept pouring out of their mouths.

Revelation 16:1-21

Then I heard a loud voice from the sanctuary say to the seven angels: "Go and empty the seven bowls of God's wrath upon the earth."

Treasury of Scripture Knowledge

Summary

Therefore he hath poured upon him the fury of his anger, and the strength of battle: and it hath set him on fire round about, yet he knew not; and it burned him, yet he laid it not to heart.

General references

Bible References

He knew

Revelation 9:18
One-third of mankind was killed by these three plagues: the fire, smoke, and sulphur that kept pouring out of their mouths.
Revelation 16:9
so that men were severely scorched, but they only cursed the name of God who had authority over these plagues, and would not repent and give Him glory.

General references

Matthew 24:39
and knew nothing about it until the Flood came and swept them all away, so it will be at the coming of the Son of Man.