Revelation 9:18-21

And by these three things, by the fire, and by the smoke, and by the brimstone, which came out of their mouths, the third part of men were killed.

Revelation 16:1-21

And I heard a great voice from the temple, saying to the seven angels, Go and pour out the vials of the wrath of God upon the earth.

Treasury of Scripture Knowledge

Summary

Therefore he hath poured upon him the fury of his anger, and the strength of battle: and it hath set him on fire round about, yet he knew not; and it burned him, yet he laid it not to heart.

General references

Bible References

He knew

Revelation 9:18
And by these three things, by the fire, and by the smoke, and by the brimstone, which came out of their mouths, the third part of men were killed.
Revelation 16:9
And men were scorched with great heat, and they blasphemed the name of God, who hath power over these plagues, and they repented not to give Him glory.

General references

Matthew 24:39
and knew not of it till the deluge came and took them all away; so shall be also the coming of the Son of man.