'Holy Covenant' in the Bible

Then he (Antiochus IV Epiphanes) will return to his land with great treasure (plunder); and his heart will be set against the holy covenant, and he will take action and return to his own land (Syria).

For ships of Cyprus [in Roman hands] will come against him; therefore he will be discouraged and turn back [to Israel] and carry out his rage against the holy covenant and take action; so he will return and show favoritism toward those [Jews] who abandon (break) the holy covenant [with God].