'Anguish' in the Bible

Listen carefully, I will throw her on a bed of sickness, and those who commit adultery with her [I will bring] into great anguish, unless they repent of her deeds.

She was with child (the Messiah) and she cried out, being in labor and in pain to give birth.

The fifth angel poured his bowl on the throne of the beast. Its kingdom was plunged into darkness. People gnawed on their tongues in anguish

and they blasphemed the God of heaven because of their anguish and their sores (abscesses, boils); and they did not repent of what they had done nor hate their wickedness.

To the degree that she glorified herself and reveled and gloated in her sensuality [living deliciously and luxuriously], to that same degree impose on her torment and anguish, and mourning and grief; for in her heart she boasts, ‘I sit as a queen [on a throne] and I am not a widow, and will never, ever see mourning or experience grief.’

For this reason in a single day her plagues (afflictions, calamities) will come, pestilence and mourning and famine, and she will be burned up with fire and completely consumed; for strong and powerful is the Lord God who judges her.

and He will wipe away every tear from their eyes; and there will no longer be death; there will no longer be sorrow and anguish, or crying, or pain; for the former order of things has passed away.”