'Bitter' in the Bible

and the name of the star is called Wormwood, and the third of the waters doth become wormwood, and many of the men did die of the waters, because they were made bitter.

and I went away unto the messenger, saying to him, 'Give me the little scroll;' and he saith to me, 'Take, and eat it up, and it shall make thy belly bitter, but in thy mouth it shall be sweet -- as honey.'

And I took the little scroll out of the hand of the messenger, and did eat it up, and it was in my mouth as honey -- sweet, and when I did eat it -- my belly was made bitter;