'Appointed' in the Bible

and saying, “The [appointed period of] time is fulfilled, and the kingdom of God is at hand; repent [change your inner self—your old way of thinking, regret past sins, live your life in a way that proves repentance; seek God’s purpose for your life] and believe [with a deep, abiding trust] in the good news [regarding salvation].”

And He appointed twelve [disciples], so that they would be with Him [for instruction] and so that He could send them out to preach [the gospel as apostles—that is, as His special messengers, personally chosen representatives],