'Destruction' in the Bible

Mordecai told him all that had happened to him, and the exact amount of money that Haman had promised to pay to the king’s treasuries for the destruction of the Jews.

He also gave him a copy of the text of the edict which had been issued in Susa for their destruction, that he might show Esther and inform her, and to order her to go in to the king to implore his favor and to plead with him for her people.

For how can I endure to see the calamity which will befall my people, and how can I endure to see the destruction of my kindred?”