Ecclesiastes 2:23

but heaviness, sorrow and disquietness all the days of his life? Insomuch that his heart cannot rest in the night. Is not this also a vain thing?

Job 5:7

but it is man, that is born unto misery, like as the sparks fly up out of the hot coals.

Job 14:1

Man that is born of a woman hath but a short time to live, and is full of divers miseries.

Psalm 127:2

It is but lost labour that ye rise up early, and take no rest, but eat the bread of carefulness; for so he giveth his beloved sleep.

Genesis 47:9

And Jacob said unto Pharaoh, "The days of my pilgrimage are a hundred and thirty years. Few and evil have the days of my life been, and have not attained unto the years of the life of my fathers in the days of their pilgrimages."

Esther 6:1

The same night could not the king sleep, and he commanded to bring the Chronicles and the stories: which when they were read before the king,

Job 7:13-14

When I think, 'My bed shall comfort me; I shall have some refreshing by talking to myself upon my couch,'

Psalm 6:6-7

I am weary of my groaning; every night wash I my bed, and water my couch with my tears.

Psalm 32:4

For thy hand is heavy upon me both day and night, and my moisture is like the drought in Summer. Selah.

Psalm 77:2-4

In the time of my trouble I sought the LORD, I held up mine hands to him in the night season, for my soul refused all other comfort.

Psalm 90:7-10

For we consume away in thy displeasure, and are afraid at thy wrathful indignation.

Psalm 90:15

Comfort us again, now after the time that thou hast plagued us, and for the years wherein we have suffered adversity.

Ecclesiastes 1:18

For where much wisdom is, there is also great travail and disquietness; and the more knowledge a man hath, the more is his care.

Ecclesiastes 5:12

A labouring man sleepeth sweetly, whether it be little or much that he eateth; but the abundance of the rich will not suffer him to sleep.

Daniel 6:18

So the king went in to his palace, and kept him sober all night, so that there was no table spread before him, neither could he take any sleep.

Acts 14:22

and strengthened the disciples souls: exhorting them to continue in the faith, affirming that we must through much tribulation enter into the kingdom of God.

Treasury of Scripture Knowledge

Summary

For all his days are sorrows, and his travail grief; yea, his heart taketh not rest in the night. This is also vanity.

General references

Bible References

His heart

Ecclesiastes 5:12
A labouring man sleepeth sweetly, whether it be little or much that he eateth; but the abundance of the rich will not suffer him to sleep.
Esther 6:1
The same night could not the king sleep, and he commanded to bring the Chronicles and the stories: which when they were read before the king,
Job 7:13
When I think, 'My bed shall comfort me; I shall have some refreshing by talking to myself upon my couch,'
Psalm 6:6
I am weary of my groaning; every night wash I my bed, and water my couch with my tears.
Psalm 32:4
For thy hand is heavy upon me both day and night, and my moisture is like the drought in Summer. Selah.
Psalm 77:2
In the time of my trouble I sought the LORD, I held up mine hands to him in the night season, for my soul refused all other comfort.
Daniel 6:18
So the king went in to his palace, and kept him sober all night, so that there was no table spread before him, neither could he take any sleep.
Acts 14:22
and strengthened the disciples souls: exhorting them to continue in the faith, affirming that we must through much tribulation enter into the kingdom of God.

General references

Ecclesiastes 1:2
All is but vanity - sayeth the Preacher - all is but plain vanity.
Ecclesiastes 3:9
What else hath a man that doth anything, but weariness and labour?