'Inconsequential' in the Bible

"So now, our God -- the great, powerful, and awesome God, who keeps covenant fidelity -- do not regard as inconsequential all the hardship that has befallen us -- our kings, our leaders, our priests, our prophets, our ancestors, and all your people -- from the days of the kings of Assyria until this very day!

Are God's encouragements inconsequential to you, even a word that has been spoken gently to you?