'Laden' in the Bible

Come unto me, all ye that labor and are heavy laden, and I will give you rest.

For of these are they that creep into houses, and take captive silly women laden with sins, led away by divers lusts,

And there came one of the seven angels who had the seven bowls, who were laden with the seven last plagues; and he spake with me, saying, Come hither, I will show thee the bride, the wife of the Lamb.