Moreover Manasseh shed very much innocent blood till he had filled Jerusalem from one end to another, besides his sin with which he made Judah to sin in doing that which was evil in the sight of LORD.

So ye shall not pollute the land in which ye are, for blood, it pollutes the land. And no expiation can be made for the land for the blood that is shed in it, but by the blood of him who shed it.

that innocent blood not be shed in the midst of thy land, which LORD thy God gives thee for an inheritance, and so blood be upon thee.

Also in thy skirts is found the blood of the souls of the innocent poor. Thou did not find them breaking in. But it is because of all these things.

Because they have forsaken me, and have estranged this place, and have burned incense in it to other gods that they knew not, they and their fathers and the kings of Judah, and have filled this place with the blood of innocents,

He filled

and shed innocent blood, even the blood of their sons and of their daughters, whom they sacrificed to the idols of Canaan. And the land was polluted with blood.

Which

Then LORD said to me, Though Moses and Samuel stood before me, yet my mind would not be toward this people. Cast them out of my sight, and let them go forth.

We have transgressed and have rebelled. Thou have not pardoned.

Therefore say to them, Thus says lord LORD: Ye eat with the blood, and lift up your eyes to your idols, and shed blood. And shall ye possess the land?

General references

that innocent blood not be shed in the midst of thy land, which LORD thy God gives thee for an inheritance, and so blood be upon thee.

also added this to them all, he even locked up John in prison.