Moreover, Manasseh shed a very great quantity of innocent blood, until he had filled Jerusalem from one end to another; besides his sin with which he made Judah sin, by doing evil in the sight of the Lord.

So you shall not pollute and defile the land in which you live; for [the shedding of innocent] blood pollutes and defiles the land. No atonement (expiation) can be made for the land for the [innocent] blood shed in it, except by the blood (execution) of him who shed it.

so that innocent blood will not be shed [by blood avengers] in your land which the Lord your God is giving you as an inheritance, and blood guilt will not be on you [for the death of an innocent man].

“Also on your skirts is found
The lifeblood of the innocent poor;
You did not find them breaking in [a house].
But in spite of all these things [your disobedience, your love of idolatry, your lack of compassion]—

Because the people [of Jerusalem] have abandoned (rejected) Me and have made this an alien and profaned place by burning sacrifices and incense in it to other gods, that neither they nor their fathers nor the kings of Judah ever knew, and because they have filled this place with the blood of the innocent

He filled

And shed innocent blood,
Even the blood of their sons and of their daughters,
Whom they sacrificed to the idols of Canaan;
And the land was polluted with their blood.

Which

Then the Lord said to me, “Even though Moses and Samuel were to stand before Me [interceding for them], My heart would still not be [turned with favor] toward this people [Judah]. Send them away from My presence and out of My sight and let them go!

We have transgressed and rebelled,
You have not pardoned.

Therefore say to them, ‘Thus says the Lord God, “You eat meat with the blood in it and raise your eyes to your idols and shed blood. Should you take possession of the land?

General references

he also added this to them all: he locked up John in prison.