Ecclesiastes 1:18

for, in abundance of wisdom is abundance of sadness, and he who addeth knowledge addeth pain.'

Job 28:28

And He saith to man: -- 'Lo, fear of the Lord, that is wisdom, And to turn from evil is understanding.'

Ecclesiastes 2:15

and I said in my heart, 'As it happeneth with the fool, it happeneth also with me, and why am I then more wise?' And I spake in my heart, that also this is vanity:

Ecclesiastes 2:23

For all his days are sorrows, and his travail sadness; even at night his heart hath not lain down; this also is vanity.

Ecclesiastes 7:16

Be not over-righteous, nor show thyself too wise, why art thou desolate?

Ecclesiastes 12:12-13

And further, from these, my son, be warned; the making of many books hath no end, and much study is a weariness of the flesh.

1 Corinthians 3:18-20

Let no one deceive himself; if any one doth seem to be wise among you in this age -- let him become a fool, that he may become wise,

James 3:13-17

Who is wise and intelligent among you? let him shew out of the good behaviour his works in meekness of wisdom,

Treasury of Scripture Knowledge

Summary

For in much wisdom is much grief: and he that increaseth knowledge increaseth sorrow.

Bible References

For in

Ecclesiastes 2:15
and I said in my heart, 'As it happeneth with the fool, it happeneth also with me, and why am I then more wise?' And I spake in my heart, that also this is vanity:
Ecclesiastes 7:16
Be not over-righteous, nor show thyself too wise, why art thou desolate?
Ecclesiastes 12:12
And further, from these, my son, be warned; the making of many books hath no end, and much study is a weariness of the flesh.
Job 28:28
And He saith to man: -- 'Lo, fear of the Lord, that is wisdom, And to turn from evil is understanding.'
1 Corinthians 3:18
Let no one deceive himself; if any one doth seem to be wise among you in this age -- let him become a fool, that he may become wise,
James 3:13
Who is wise and intelligent among you? let him shew out of the good behaviour his works in meekness of wisdom,

General references

Ecclesiastes 1:14
I have seen all the works that have been done under the sun, and lo, the whole is vanity and vexation of spirit!
Ecclesiastes 6:11
For there are many things multiplying vanity; what advantage is to man?