Ecclesiastes 2:23

All his days are sorrow, and his work is full of grief. Even in the night his heart has no rest. This again is vanity.

Job 5:7

A person is born for trouble as surely as sparks fly up from a fire.

Job 14:1

Man born of woman, lives a short life that is full of trouble.

Psalm 127:2

It is vain to work hard for the food you eat by getting up early and going to bed late. Jehovah gives food to those he loves while they sleep.

Genesis 47:9

Jacob answered: My life of wandering has lasted a hundred and thirty years. Those years have been few and difficult, unlike the long years of my ancestors in their wanderings.

Esther 6:1

That night the king was unable to get any sleep. He sent for the books of the records and had some one was read them to him.

Job 7:13-14

When I think: 'My bed will comfort me, and I will try to forget my misery with sleep,

Psalm 6:6-7

I am worn out from groaning. All night long I flood my bed with weeping and drench my couch with tears.

Psalm 32:4

Day and night your hand lay heavily on me. My strength drained in the summer heat.

Psalm 77:2-4

In the day of my trouble I sought Jehovah. My hand was stretched out in the night, and did not get tired. I refused to be comforted.

Psalm 90:7-10

Your anger consumes us. We are troubled by your rage.

Psalm 90:15

Make us rejoice for as many days as you have made us suffer, for as many years as we have experienced evil.

Ecclesiastes 1:18

In much wisdom there is much grief for he who increases knowledge increases pain.

Ecclesiastes 5:12

The sleep of the workingman is pleasant, whether he eats little or much. However the full stomach of the rich man does not allow him to sleep.

Daniel 6:18

The king went to his palace and did not eat. He refused musical entertainment and he could not sleep.

Acts 14:22

They strengthened the disciples and encouraged them to continue in the faith. They said, We must enter the kingdom of God through much tribulation.

Treasury of Scripture Knowledge

Summary

For all his days are sorrows, and his travail grief; yea, his heart taketh not rest in the night. This is also vanity.

General references

Bible References

His heart

Ecclesiastes 5:12
The sleep of the workingman is pleasant, whether he eats little or much. However the full stomach of the rich man does not allow him to sleep.
Esther 6:1
That night the king was unable to get any sleep. He sent for the books of the records and had some one was read them to him.
Job 7:13
When I think: 'My bed will comfort me, and I will try to forget my misery with sleep,
Psalm 6:6
I am worn out from groaning. All night long I flood my bed with weeping and drench my couch with tears.
Psalm 32:4
Day and night your hand lay heavily on me. My strength drained in the summer heat.
Psalm 77:2
In the day of my trouble I sought Jehovah. My hand was stretched out in the night, and did not get tired. I refused to be comforted.
Daniel 6:18
The king went to his palace and did not eat. He refused musical entertainment and he could not sleep.
Acts 14:22
They strengthened the disciples and encouraged them to continue in the faith. They said, We must enter the kingdom of God through much tribulation.

General references

Ecclesiastes 1:2
Vanity of vanities, said the Preacher, vanity of vanities; all is vanity.
Ecclesiastes 3:9
What profit is there to the worker in his work?