Genesis 17:20

As for Ishmael, I have heard and listened to you; behold, I will bless him, and will make him fruitful and will greatly multiply him [through his descendants]. He will be the father of twelve princes (chieftains, sheiks), and I will make him a great nation.

Genesis 21:18

Get up, help the boy up, and hold him by the hand, for I will make him a great nation.”

Genesis 21:13

And I will also make a nation of [Ishmael] the son of the maid, because he is your descendant.”

Genesis 16:10-12

Then the Angel of the Lord said to her, “I will greatly multiply your descendants so that they will be too many to count.”

Genesis 25:12-18

Now these are the records of the descendants of Ishmael, Abraham’s son, whom Hagar the Egyptian, Sarah’s maid, bore to Abraham;

Treasury of Scripture Knowledge

Summary

And as for Ishmael, I have heard thee: Behold, I have blessed him, and will make him fruitful, and will multiply him exceedingly; twelve princes shall he beget, and I will make him a great nation.

I have blessed

Twelve

Bible References

I have blessed

Genesis 16:10
Then the Angel of the Lord said to her, “I will greatly multiply your descendants so that they will be too many to count.”

Twelve

Genesis 25:12
Now these are the records of the descendants of Ishmael, Abraham’s son, whom Hagar the Egyptian, Sarah’s maid, bore to Abraham;

And i

Genesis 21:13
And I will also make a nation of [Ishmael] the son of the maid, because he is your descendant.”

General references

Genesis 1:28
And God blessed them [granting them certain authority] and said to them, “Be fruitful, multiply, and fill the earth, and subjugate it [putting it under your power]; and rule over (dominate) the fish of the sea, the birds of the air, and every living thing that moves upon the earth.”
Genesis 13:16
I will make your descendants [as numerous] as the dust of the earth, so that if a man could count the [grains of] dust of the earth, then your descendants could also be counted.
Genesis 21:13
And I will also make a nation of [Ishmael] the son of the maid, because he is your descendant.”
Genesis 25:12
Now these are the records of the descendants of Ishmael, Abraham’s son, whom Hagar the Egyptian, Sarah’s maid, bore to Abraham;