Genesis 26:35

And {they made life bitter} for Isaac and Rebekah.

Genesis 6:2

Then the sons of God saw the daughters of humankind, that they [were] beautiful. And they took for themselves wives from all that they chose.

Genesis 27:46-2

Then Rebekah said to Isaac, "I loathe my life because of the Hittite women. If Jacob takes a wife from Hittite women like these, from the {native women}, {what am I living for}?"

Genesis 28:8

Then Esau saw that the daughters of Canaan [were] evil in the eyes of Isaac his father,

Treasury of Scripture Knowledge

Summary

Which were a grief of mind unto Isaac and to Rebekah.

General references

Bible References

Which

Genesis 6:2
Then the sons of God saw the daughters of humankind, that they [were] beautiful. And they took for themselves wives from all that they chose.
Genesis 27:46
Then Rebekah said to Isaac, "I loathe my life because of the Hittite women. If Jacob takes a wife from Hittite women like these, from the {native women}, {what am I living for}?"
Genesis 28:1
Then Isaac called Jacob and blessed him. And he instructed him and said to him, "You must not take a wife from the daughters of Canaan.

General references

Genesis 34:9
Make marriages with us. Give us your daughters and take our daughters for yourselves.