Mark 10:6

God made male and female from the beginning of creation.

Genesis 1:27

God created man in his own image. In the image of God he created him. He created male and female.

Genesis 5:2

He created them male and female and blessed them. When they were created, he called them Mankind.

2 Peter 3:4

Saying, Where is the promise of his coming? For, from the day that the fathers fell asleep [in death], all things continue as they were from the beginning of the creation.

Genesis 1:1

In the beginning God created the heavens and the earth.

Genesis 2:20-23

So the man gave names to all the livestock, the birds of the air and all the beasts of the field. But no suitable helper was found for Adam.

Malachi 2:14-16

You ask: Why do you not accept our offerings? It is because Jehovah is a witness between you and the wife of your youth. The one to whom you have been unfaithful! She is your companion, the wife of your marriage vows.

Mark 13:19

The tribulation in these days will be greater then there has ever been from the beginning of God's creation until now, and never shall be.

Treasury of Scripture Knowledge

Summary

But from the beginning of the creation God made them male and female.

The beginning

Bible References

The beginning

Genesis 1:1
In the beginning God created the heavens and the earth.
2 Peter 3:4
Saying, Where is the promise of his coming? For, from the day that the fathers fell asleep [in death], all things continue as they were from the beginning of the creation.

God

Genesis 1:27
God created man in his own image. In the image of God he created him. He created male and female.
Genesis 2:20
So the man gave names to all the livestock, the birds of the air and all the beasts of the field. But no suitable helper was found for Adam.
Genesis 5:2
He created them male and female and blessed them. When they were created, he called them Mankind.
Malachi 2:14
You ask: Why do you not accept our offerings? It is because Jehovah is a witness between you and the wife of your youth. The one to whom you have been unfaithful! She is your companion, the wife of your marriage vows.