Mark 13:19

for at that time there will be such tribulation as has not occurred, from the beginning of the creation which God made, until now—and never will [be again].

Daniel 12:1

“Now at that [end] time Michael, the great [angelic] prince who stands guard over the children of your people, will arise. And there will be a time of distress such as never occurred since there was a nation until that time; but at that time your people, everyone who is found written in the Book [of Life], will be rescued.

Deuteronomy 4:32

“Indeed, ask now about the days that are past, [those days] which were before you, since the day that God created man on the earth, and ask from one end of the heavens to the other. Has anything been done like this great thing, or has anything been heard like it?

Daniel 9:26

Then after the sixty-two weeks [of years] the Anointed One will be cut off [and denied His Messianic kingdom] and have nothing [and no one to defend Him], and the people of the [other] prince who is to come will destroy the city and the sanctuary. Its end will come with a flood; even to the end there will be war; desolations are determined.

Joel 2:2


A day of darkness and gloom,
A day of clouds and of thick [dark] mist,
Like the dawn spread over the mountains;
There is a [pagan, hostile] people numerous and mighty,
The like of which has never been before
Nor will be again afterward
Even for years of many generations.

Mark 10:6

But from the beginning of creation God made them male and female.

Deuteronomy 28:59

then the Lord will bring extraordinary plagues on you and your descendants, even severe and lasting plagues, and miserable and chronic sicknesses.

Deuteronomy 29:22-28

Now the next generation, your children who come after you and the foreigner who comes from a distant land, when they see the plagues of this land and the diseases with which the Lord has afflicted it, will say,

Isaiah 65:12-15


I will destine you for the sword, [says the Lord],
And all of you will bow down to the slaughter,
Because when I called, you did not answer;
When I spoke, you did not listen or obey.
But you did [what was] evil in My sight
And chose that in which I did not delight.”

Lamentations 1:12


“Is it nothing to you, all you who pass this way?
Look and see if there is any pain like my pain
Which was severely dealt out to me,
Which the Lord has inflicted [on me] on the day of His fierce anger.

Lamentations 2:13


How shall I console you?
To what shall I compare you,
O Daughter of Jerusalem?
With what shall I compare you, so that I may comfort you,
O Virgin Daughter of Zion?
For your ruin is as vast as the sea;
Who can heal you?

Lamentations 4:6


For the [punishment of the] wickedness of the daughter of my people [Jerusalem]
Is greater than the [punishment for the] sin of Sodom,
Which was overthrown in a moment,
And no hands were turned toward her [to offer help].

Daniel 9:12

And He has carried out completely His [threatening] words which He had spoken against us and against our rulers [the kings, princes, and judges] who ruled us, to bring on us a great tragedy; for under the whole heaven there has not been done anything [so dreadful] like that which [He commanded and] was done to Jerusalem.

Matthew 24:21

For at that time there will be a great tribulation (pressure, distress, oppression), such as has not occurred since the beginning of the world until now, nor ever will [again].

Luke 21:22-24

for these are days of vengeance [of rendering full justice or satisfaction], so that all things which are written will be fulfilled.

Treasury of Scripture Knowledge

Summary

For in those days shall be affliction, such as was not from the beginning of the creation which God created unto this time, neither shall be.

General references

Bible References

In those

Deuteronomy 28:59
then the Lord will bring extraordinary plagues on you and your descendants, even severe and lasting plagues, and miserable and chronic sicknesses.
Deuteronomy 29:22
Now the next generation, your children who come after you and the foreigner who comes from a distant land, when they see the plagues of this land and the diseases with which the Lord has afflicted it, will say,
Isaiah 65:12

I will destine you for the sword, [says the Lord],
And all of you will bow down to the slaughter,
Because when I called, you did not answer;
When I spoke, you did not listen or obey.
But you did [what was] evil in My sight
And chose that in which I did not delight.”
Lamentations 1:12

“Is it nothing to you, all you who pass this way?
Look and see if there is any pain like my pain
Which was severely dealt out to me,
Which the Lord has inflicted [on me] on the day of His fierce anger.
Lamentations 2:13

How shall I console you?
To what shall I compare you,
O Daughter of Jerusalem?
With what shall I compare you, so that I may comfort you,
O Virgin Daughter of Zion?
For your ruin is as vast as the sea;
Who can heal you?
Lamentations 4:6

For the [punishment of the] wickedness of the daughter of my people [Jerusalem]
Is greater than the [punishment for the] sin of Sodom,
Which was overthrown in a moment,
And no hands were turned toward her [to offer help].
Daniel 9:12
And He has carried out completely His [threatening] words which He had spoken against us and against our rulers [the kings, princes, and judges] who ruled us, to bring on us a great tragedy; for under the whole heaven there has not been done anything [so dreadful] like that which [He commanded and] was done to Jerusalem.
Daniel 12:1
“Now at that [end] time Michael, the great [angelic] prince who stands guard over the children of your people, will arise. And there will be a time of distress such as never occurred since there was a nation until that time; but at that time your people, everyone who is found written in the Book [of Life], will be rescued.
Joel 2:2

A day of darkness and gloom,
A day of clouds and of thick [dark] mist,
Like the dawn spread over the mountains;
There is a [pagan, hostile] people numerous and mighty,
The like of which has never been before
Nor will be again afterward
Even for years of many generations.
Matthew 24:21
For at that time there will be a great tribulation (pressure, distress, oppression), such as has not occurred since the beginning of the world until now, nor ever will [again].
Luke 21:22
for these are days of vengeance [of rendering full justice or satisfaction], so that all things which are written will be fulfilled.

From

Deuteronomy 4:32
“Indeed, ask now about the days that are past, [those days] which were before you, since the day that God created man on the earth, and ask from one end of the heavens to the other. Has anything been done like this great thing, or has anything been heard like it?

General references

Deuteronomy 28:59
then the Lord will bring extraordinary plagues on you and your descendants, even severe and lasting plagues, and miserable and chronic sicknesses.