Mark 13:19

for there will be such misery at that time as has never been since the beginning of God's creation, and never will be again.

But from the beginning of the creation, 'God made them male and female.

for there will be greater misery at that time than ever has been since the world began, or ever will be again.

for these are the days of vengeance when all that is written in the Scriptures will be fulfilled.

Treasury of Scripture Knowledge

For in those days shall be affliction, such as was not from the beginning of the creation which God created unto this time, neither shall be.

for there will be greater misery at that time than ever has been since the world began, or ever will be again.

for these are the days of vengeance when all that is written in the Scriptures will be fulfilled.