Revelation 16:2

The first angel went and emptied his bowl upon the earth; and it turned to loathsome and painful sores upon all who bore the brand of the Beast and who worshiped its image.

Revelation 8:7

The first blew; and there came hail and fire mixed with blood, and it fell upon the earth. A third part of the earth was burnt up, and a third of the trees, and every blade of grass.

Luke 16:20-22

Near his gateway there had been laid a beggar named Lazarus, who was covered with sores,

Acts 12:23

Instantly an angel of the Lord struck him, because he did not give God the glory; and he was attacked with worms, and died.

Revelation 13:15-18

It was permitted to breathe life into the image of the Beast, so that the image of the Beast might speak; and it was also permitted to cause all who refused to worship the image of the Beast to be put to death.

Revelation 14:16

He who was sitting on the cloud brought his sickle down upon the earth, and the Harvest of Earth was reaped.

Revelation 16:11

and blasphemed the God of Heaven, because of their pains and because of their sores; yet they did not repent of what they had done.

Treasury of Scripture Knowledge

Summary

And the first went, and poured out his vial upon the earth; and there fell a noisome and grievous sore upon the men which had the mark of the beast, and upon them which worshipped his image.

Bible References

Upon the earth

Revelation 8:7
The first blew; and there came hail and fire mixed with blood, and it fell upon the earth. A third part of the earth was burnt up, and a third of the trees, and every blade of grass.
Revelation 14:16
He who was sitting on the cloud brought his sickle down upon the earth, and the Harvest of Earth was reaped.

A noisome

Luke 16:20
Near his gateway there had been laid a beggar named Lazarus, who was covered with sores,
Acts 12:23
Instantly an angel of the Lord struck him, because he did not give God the glory; and he was attacked with worms, and died.

Had

Revelation 13:15
It was permitted to breathe life into the image of the Beast, so that the image of the Beast might speak; and it was also permitted to cause all who refused to worship the image of the Beast to be put to death.