'Deeply' in the Bible

And [although he] was deeply grieved, the king, because of his oaths and {dinner guests}, did not want to refuse her.

And sighing deeply in his spirit, he said, "Why does this generation demand a sign? Truly I say to you, no sign will be given to this generation!"

And he said to them, "My soul is deeply grieved, to the point of death. Remain here and stay awake."