'Affliction' in the Bible

Then the Angel of the Lord said to her:You have conceived and will have a son.You will name him Ishmael,for the Lord has heard your cry of affliction.

Leah conceived, gave birth to a son, and named him Reuben, for she said, “The Lord has seen my affliction; surely my husband will love me now.”

If the God of my father, the God of Abraham, the Fear of Isaac, had not been with me, certainly now you would have sent me off empty-handed. But God has seen my affliction and my hard work, and He issued His verdict last night.”

And the second son he named Ephraim, meaning, “God has made me fruitful in the land of my affliction.”