'Depressed' in the Bible

For while we are in this tent, we groan, being burdened [often weighed down, oppressed], not that we want to be unclothed [separated by death from the body], but to be clothed, so that what is mortal [the body] will be swallowed up by life [after the resurrection].

But God, who comforts and encourages the depressed and the disquieted, comforted us by the arrival of Titus.