'Depressed' in the Bible

but for Cain and his offering He had no respect. So Cain became extremely angry (indignant), and he looked annoyed and hostile.

And the Lord said to Cain, “Why are you so angry? And why do you look annoyed?

When Joseph came to them in the morning and looked at them, [he saw that] they were sad and depressed.

The priest shall look at the diseased spot on the skin of his body, and if the hair in the infection has turned white and the infection appears deeper than the skin of his body, it is an infection of leprosy; when the priest has looked at him, he shall pronounce him [ceremonially] unclean.

If the bright spot is white on the skin of his body and does not appear to be deeper than the skin, and the hair on it has not turned white, the priest shall isolate the person who has the infection for seven days.

He shall examine the mark, and if the mark on the walls of the house has greenish or reddish depressions and appears deeper than the surface,

Then they set out from Mount Hor by the way of the [branch of the] Red Sea [called the Gulf of Aqabah], to go around the land of Edom; and the people became impatient, because [of the challenges] of the journey.

It is the Lord who goes before you; He will be with you. He will not fail you or abandon you. Do not fear or be dismayed.”

So Ahab [already upset by the Lord’s message] came into his house [feeling more] resentful and sullen because of what Naboth the Jezreelite had said to him; for he had said, “I will not give you the inheritance of my fathers.” And he lay down on his bed and turned away his face, and would not eat any food.

Then Ezra said to them, “Go [your way], eat the rich festival food, drink the sweet drink, and send portions to him for whom nothing is prepared; for this day is holy to our Lord. And do not be worried, for the joy of the Lord is your strength and your stronghold.”

“Do not fear, for you will not be put to shame,And do not feel humiliated or ashamed, for you will not be disgraced.For you will forget the shame of your youth,And you will no longer remember the disgrace of your widowhood.

And taking with Him Peter and the two sons of Zebedee [James and John], He began to be grieved and greatly distressed.

He took Peter and James and John with Him, and He began to be deeply distressed and troubled [extremely anguished at the prospect of what was to come].

“But be on guard, so that your hearts are not weighed down and depressed with the giddiness of debauchery and the nausea of self-indulgence and the worldly worries of life, and then that day [when the Messiah returns] will not come on you suddenly like a trap;

So for now you are in grief; but I will see you again, and [then] your hearts will rejoice, and no one will take away from you your [great] joy.

For while we are in this tent, we groan, being burdened [often weighed down, oppressed], not that we want to be unclothed [separated by death from the body], but to be clothed, so that what is mortal [the body] will be swallowed up by life [after the resurrection].

But God, who comforts and encourages the depressed and the disquieted, comforted us by the arrival of Titus.