'Despised' in the Bible

He answered them, “Elijah does come first and restores and reestablishes all things. And yet how is it written of the Son of Man that He will suffer many things [grief and physical distress] and be treated with contempt [utterly despised and rejected]?

and you will be continually hated by everyone because of [your association with] My name.

This Jesus is the stone which was despised and rejected by you, the builders, but which became the chief Cornerstone.

But as at that time the child [of ordinary birth] born according to the flesh persecuted the son who was born according to [the promise and working of] the Spirit, so it is now also.