'Distress' in the Bible

[There will be] affliction and distress for every {human being} who does evil, of the Jew first and of the Greek,

destruction and distress [are] in their paths,

Who will separate us from the love of Christ? [Will] affliction or distress or persecution or hunger or lack of sufficient clothing or danger or the sword?

that my grief is great and [there is] constant distress in my heart.