'Issue' in the Bible

And, behold, a woman, which was diseased with an issue of blood twelve years, came behind him, and touched the hem of his garment:

Now there were with us seven brethren: and the first, when he had married a wife, deceased, and, having no issue, left his wife unto his brother:

And a certain woman, which had an issue of blood twelve years,

And a woman having an issue of blood twelve years, which had spent all her living upon physicians, neither could be healed of any,

Came behind him, and touched the border of his garment: and immediately her issue of blood stanched.