'Transgression' in the Bible
Because of the transgression [of God’s people—their irreverence and ungodliness] the host will be given over to the wicked horn, along with the regular sacrifice; and righteousness and truth will be flung to the ground, and the horn will do as it pleases [by divine permission] and prosper.
Then I heard a holy one (angel) speaking, and another holy one said to the one who was speaking, “How much time will be required to complete the vision regarding the regular sacrifice, the transgression that brings horror, and the trampling underfoot of both the sanctuary and the host [of the people]?”
“Seventy weeks [of years, or 490 years] have been decreed for your people and for your holy city (Jerusalem), to finish the transgression, to make an end of sins, to make atonement (reconciliation) for wickedness, to bring in everlasting righteousness (right-standing with God), to seal up vision and prophecy and prophet, and to anoint the Most Holy Place.