45 Bible Verses about Despair

Most Relevant Verses

Psalm 40:2


He brought me up out of a horrible pit [of tumult and of destruction], out of the miry clay,
And He set my feet upon a rock, steadying my footsteps and establishing my path.

2 Corinthians 1:8

For we do not want you to be uninformed, brothers and sisters, about our trouble in [the west coast province of] Asia [Minor], how we were utterly weighed down, beyond our strength, so that we despaired even of life [itself].

Job 6:26


“Do you intend to reprove my words [with a convincing argument],
When the words of one in despair belong to the wind [and go ignored]?

Psalm 27:13


I would have despaired had I not believed that I would see the goodness of the Lord
In the land of the living.

2 Corinthians 2:7

so instead [of further rebuke, now] you should rather [graciously] forgive and comfort and encourage him, to keep him from being overwhelmed by excessive sorrow.

Ecclesiastes 2:20

So I turned aside and let my heart despair over all the fruit of my labor for which I had labored under the sun.

2 Corinthians 1:9

Indeed, we felt within ourselves that we had received the sentence of death [and were convinced that we would die, but this happened] so that we would not trust in ourselves, but in God who raises the dead.

Psalm 88:15


I was afflicted and close to death from my youth on;
I suffer Your terrors; I am overcome.

Psalm 43:5


Why are you in despair, O my soul?
And why are you restless and disturbed within me?
Hope in God and wait expectantly for Him, for I shall again praise Him,
The help of my [sad] countenance and my God.

Jeremiah 17:16


But as for me, I have not tried to escape from being a shepherd [walking] after You,
Nor have I longed for the woeful day [of judgment];
You know that, whatever I said
Was [spoken] in Your presence and was from You.

Job 6:14


“For the despairing man there should be kindness from his friend;
So that he does not abandon (turn away from) the fear of the Almighty.

Psalm 42:11


Why are you in despair, O my soul?
Why have you become restless and disquieted within me?
Hope in God and wait expectantly for Him, for I shall yet praise Him,
The help of my countenance and my God.

Isaiah 61:3


To grant to those who mourn in Zion the following:
To give them a turban instead of dust [on their heads, a sign of mourning],
The oil of joy instead of mourning,
The garment [expressive] of praise instead of a disheartened spirit.
So they will be called the trees of righteousness [strong and magnificent, distinguished for integrity, justice, and right standing with God],
The planting of the Lord, that He may be glorified.

2 Corinthians 1:10

He rescued us from so great a threat of death, and will continue to rescue us. On Him we have set our hope. And He will again rescue us [from danger and draw us near],

Psalm 42:5


Why are you in despair, O my soul?
And why have you become restless and disturbed within me?
Hope in God and wait expectantly for Him, for I shall again praise Him
For the help of His presence.

Ezekiel 4:16

Moreover, He said to me, “Son of man, behold (listen carefully), I am going to break the staff of bread [that supports life] in Jerusalem; and they shall eat bread [rationed] by weight and [eat it] with anxiety and fear, and drink water by measure and [drink it] in horror [of the impending starvation],

Isaiah 9:1

But there will be no more gloom for her who was in anguish [for with judgment comes the promise of salvation]. In earlier times He treated the land of Zebulun and the land of Naphtali with contempt, but later on He will make them honored [by the presence of the Messiah], by the way of the sea, on the other side of Jordan, Galilee of the Gentiles.

Job 9:23


“When [His] scourge kills suddenly,
He mocks at the despair of the innocent.

Psalm 130:1

Out of the depths [of distress] I have cried to You, O Lord.

Psalm 18:6


In my distress [when I seemed surrounded] I called upon the Lord
And cried to my God for help;
He heard my voice from His temple,
And my cry for help came before Him, into His very ears.

Psalm 61:2


From the end of the earth I call to You, when my heart is overwhelmed and weak;
Lead me to the rock that is higher than I [a rock that is too high to reach without Your help].

Ezekiel 30:3


“For the day is near,
Even the day of the Lord is near,
It will be a cloudy day;
A time of doom for the nations.

Isaiah 19:9


Moreover, those who make linen from combed flax
And those who weave white cloth will be ashamed.

1 Samuel 4:20

And about the time of her death [following the sudden birth] the women attending her said to her, “Do not be afraid, for you have given birth to a son.” But she did not answer or pay any attention.

2 Corinthians 1:12

This is our [reason for] proud confidence: our conscience testifies that we have conducted ourselves in the world [in general], and especially toward you, with pure motives and godly sincerity, not in human wisdom, but in the grace of God [that is, His gracious lovingkindness that leads people to Christ and spiritual maturity].

Proverbs 21:15


When justice is done, it is a joy to the righteous (the upright, the one in right standing with God),
But to the evildoers it is disaster.

Hosea 2:15


“Then I will give her her vineyards from there,
And make the Valley of Achor a door of hope and expectation [anticipating the time when I will restore My favor on her].
And she will sing there and respond as in the days of her youth
As in the day when she came up from the land of Egypt.

1 Samuel 27:1

But David said in his heart, “Now I will die one day by the hand of Saul. There is nothing better for me than to escape to the land of the Philistines. Then Saul will give up searching for me inside the borders of Israel, and I will escape from his hand [once and for all].”

Psalm 42:6


O my God, my soul is in despair within me [the burden more than I can bear];
Therefore I will [fervently] remember You from the land of the Jordan
And the peaks of [Mount] Hermon, from Mount Mizar.

Lamentations 3:18


So I say, “My strength has perished
And so has my hope and expectation from the Lord.”

Isaiah 57:16


“For I will not contend forever,
Nor will I always be angry;
For [if I did stay angry] the spirit [of man] would grow weak before Me,
And the breath of those whom I have created.

Ezekiel 12:19

Then say to the people of the land, ‘Thus says the Lord God concerning the inhabitants of Jerusalem in the land of Israel, “They will eat their bread with anxiety and drink their water with horror, because their land will be stripped and looted of its fullness because of the violence of all those who live in it.

Job 38:16


“Have you entered and explored the springs of the sea
Or [have you] walked in the recesses of the deep?

Psalm 142:6


“Give attention to my cry,
For I am brought very low;
Rescue me from my persecutors,
For they are stronger than I.

Deuteronomy 28:65

Among those nations you will find no peace (rest), and there will be no resting place for the sole of your foot; but there the Lord will give you a trembling heart, failing eyes, and a despairing soul.

Zephaniah 1:14


The great [judgment] day of the Lord is near,
Near and coming very quickly.
Listen! The [voice of the] day of the Lord!
The warrior cries out bitterly [unable to fight or to flee].

From Thematic Bible


Despair » General references to

Exodus 6:9

Moses told this to the Israelites, but they did not listen to him because of their impatience and despondency, and because of their forced labor.

Deuteronomy 28:34

You shall be driven mad by the sight of the things you see.

Lamentations 3:18


So I say, “My strength has perished
And so has my hope and expectation from the Lord.”

More verses: Ezekiel 37:11 Acts 27:20

Despair » Leads men to desire death

Numbers 11:15

So if this is the way You are going to deal with me, please kill me at once, if I have found favor in your sight, and do not let me see my wretchedness.”

1 Kings 19:4

But he himself traveled a day’s journey into the wilderness, and he came and sat down under a juniper tree and asked [God] that he might die. He said, “It is enough; now, O Lord, take my life, for I am no better than my fathers.”

Job 3:21


Who wait for death, but it does not come,
And dig (search) for death more [diligently] than for hidden treasures,

Job 7:15


So that I would choose suffocation,
Death rather than my pain.

Jeremiah 8:3

And death will be chosen rather than life by all the remnant of those who remain of this evil family (nation), who remain in all the places to which I have driven them,” says the Lord of hosts.

More verses: Jonah 4:3 Revelation 9:6

Despair » Sometimes drives men to suicide

2 Samuel 17:23

Now when Ahithophel saw that his advice had not been followed, he saddled his donkey and set out and went to his home, to his city. Then he put his household in order, and hanged himself. So he died and was buried in the tomb of his father.

Acts 1:18

(Now Judas Iscariot acquired a piece of land [indirectly] with the [money paid him as a] reward for his treachery, and falling headlong, his body burst open in the middle and all his intestines poured out.

1 Kings 16:18

When Zimri saw that the city was taken, he went into the fortress of the king’s palace; and while inside, he set fire to the king’s palace and died,

1 Samuel 31:4

Saul said to his armor bearer, “Draw your sword and pierce me through with it, otherwise these uncircumcised [Philistines] will come and pierce me through and abuse and mock me.” But his armor bearer would not, because he was terrified [of doing such a thing]. So Saul took his sword and fell on it.

Despair » Produced in the wicked by divine judgments

Deuteronomy 28:34

You shall be driven mad by the sight of the things you see.

Deuteronomy 28:67

In the morning you will say, ‘I wish it were evening!’ and in the evening you will say, ‘I wish it were morning!’—because of the dread in your heart with which you tremble, and because of the sight of your eyes which you will see.

Despair » Leads to » Blasphemy

Isaiah 8:21

They [who consult mediums and soothsayers] will pass through the land deeply distressed and hungry, and when they are hungry, they will become enraged and will curse their king and their God as they look upward.

Revelation 16:10-11

Then the fifth [angel] emptied his bowl on the throne of the beast, and his kingdom was [plunged] in darkness; and people gnawed their tongues for the torment [of their excruciating distress and severe pain] And blasphemed the God of heaven because of their anguish and their ulcers (sores), and they did not deplore their wicked deeds or repent [for what they had done].

Despair » Leads to » Continuing in sin

Jeremiah 2:25


“[Cease your mad running after idols to]
Keep your feet from becoming bare
And your throat from becoming dry;
But you said, ‘It is hopeless!
For I have loved strangers and foreign gods,
And I will walk after them.’

Jeremiah 18:12

But they will say, ‘That is hopeless! For we are going to follow our own plans, and each of us will act in accordance with the stubbornness of his evil heart.’

Despair » Saints sometimes tempted to

Lamentations 3:18


So I say, “My strength has perished
And so has my hope and expectation from the Lord.”

Despair » Trust in God, a preservative against

Psalm 42:11


Why are you in despair, O my soul?
Why have you become restless and disquieted within me?
Hope in God and wait expectantly for Him, for I shall yet praise Him,
The help of my countenance and my God.

Psalm 42:5


Why are you in despair, O my soul?
And why have you become restless and disturbed within me?
Hope in God and wait expectantly for Him, for I shall again praise Him
For the help of His presence.

Despair » Saints enabled to overcome

2 Corinthians 4:8-9

We are hedged in (pressed) on every side [troubled and oppressed in every way], but not cramped or crushed; we suffer embarrassments and are perplexed and unable to find a way out, but not driven to despair; We are pursued (persecuted and hard driven), but not deserted [to stand alone]; we are struck down to the ground, but never struck out and destroyed;

Despair » Exemplified » Cain

Genesis 4:13-14

Then Cain said to the Lord, My punishment is greater than I can bear. Behold, You have driven me out this day from the face of the land, and from Your face I will be hidden; and I will be a fugitive and a vagabond and a wanderer on the earth, and whoever finds me will kill me.

Despair » Shall seize upon the wicked at the appearing of Christ

Revelation 6:16

and they called to the mountains and the rocks, “Fall on us and hide us from the face of Him who sits on the throne, and from the [righteous] wrath and indignation of the Lamb;

Despair » Exemplified » Ahithophel

2 Samuel 17:23

Now when Ahithophel saw that his advice had not been followed, he saddled his donkey and set out and went to his home, to his city. Then he put his household in order, and hanged himself. So he died and was buried in the tomb of his father.

Despair » Exemplified » Judas

Topics on Despair

Despair, Description Of

Psalm 42:5


Why are you in despair, O my soul?
And why have you become restless and disturbed within me?
Hope in God and wait expectantly for Him, for I shall again praise Him
For the help of His presence.

Despair, Remedies For

Psalm 42:5


Why are you in despair, O my soul?
And why have you become restless and disturbed within me?
Hope in God and wait expectantly for Him, for I shall again praise Him
For the help of His presence.

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Theasaurus: Despair