Treasury of Scripture Knowledge

Summary

Having the understanding darkened, being alienated from the life of God through the ignorance that is in them, because of the blindness of their heart:

Bible References

The understanding

The times of ignorance God overlooked, but now he commands all people everywhere to repent,
rescuing you from the Jewish people and from the Gentiles, to whom I am sending you,
for although they knew God they did not honor him as God or give thanks to him, but they became futile in their thinking, and their foolish hearts were darkened.
For since in the wisdom of God the world through its wisdom did not know God, God was pleased through the foolishness of what was preached to save those who believe.
In their case the god of this world has blinded the minds of the unbelievers, so that they might not see the light of the gospel of the glory of Christ, who is the image of God.
Formerly, when you did not know God, you were slaves to those which by nature are no gods.
not in the passion of lust like the heathen, who do not know God;

Alienated

remember that you were at that time separate from Christ, excluded from the commonwealth of Israel, and strangers to the covenants of promise, having no hope and without God in the world.
For the mind that is set on the flesh is hostile to God; it does not submit to God's law, nor can it do so;
Formerly, when you did not know God, you were slaves to those which by nature are no gods.
And although you were once alienated and hostile in mind, doing evil deeds,
not in the passion of lust like the heathen, who do not know God;
You adulteresses, do you not know that friendship with the world is hostility toward God? Therefore whoever wishes to be a friend of the world makes himself an enemy of God.

Because

for although they knew God they did not honor him as God or give thanks to him, but they became futile in their thinking, and their foolish hearts were darkened.
and if you are sure that you are a guide to the blind, a light to those who are in darkness,
But he who hates his brother is in the darkness and walks in the darkness, and does not know where he is going, because the darkness has blinded his eyes.
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