Mark 13:19

for those days will be days of misery, the like of which has never been from the beginning of God's creation until now ??no and never shall be.

Mark 10:6

But from the beginning, when God created the world, Male and female, He created them:

Matthew 24:21

for there will be sore misery then, such as never has been from the beginning of the world till now ??no and never shall be.

Luke 21:22-24

for these are the days of the divine Vengeance, in fulfilment of all that is written in scripture.

Treasury of Scripture Knowledge

Summary

For in those days shall be affliction, such as was not from the beginning of the creation which God created unto this time, neither shall be.

Bible References

In those

Matthew 24:21
for there will be sore misery then, such as never has been from the beginning of the world till now ??no and never shall be.
Luke 21:22
for these are the days of the divine Vengeance, in fulfilment of all that is written in scripture.