Revelation 16:2

So, the first [angel] went and poured out his bowl onto the earth and a terrible and painful sore broke out on the people who had the mark of the beast and who worshiped his statue.

Revelation 8:7

[When] the first trumpet sounded [I saw] hail and fire, mingled with blood, being hurled down onto the earth. And one third of it was burned up, and one third of the trees were burned up and all the green grass was [also] burned up.

Luke 16:20-22

And a certain beggar named Lazarus, who was full of sores, was laid at the rich man's doorway.

Acts 12:23

Suddenly, an angel from God struck him [with a terrible condition] because he refused to honor God [by what he said in his speech], so he was consumed by worms and died.

Revelation 13:15-18

Now the [second] beast was given [the power] to give breath to the statue of the [first] beast, so that it could both speak and cause all those who refused to worship the statue of the [first] beast to be killed.

Revelation 14:16

And He who sat on the cloud swung His sickle onto the earth, and its crop was harvested.

Revelation 16:11

and they cursed the God of heaven because of their pains and their sores. But they [still] refused to repent of their [evil] deeds.

Treasury of Scripture Knowledge

Summary

And the first went, and poured out his vial upon the earth; and there fell a noisome and grievous sore upon the men which had the mark of the beast, and upon them which worshipped his image.

Bible References

Upon the earth

Revelation 8:7
[When] the first trumpet sounded [I saw] hail and fire, mingled with blood, being hurled down onto the earth. And one third of it was burned up, and one third of the trees were burned up and all the green grass was [also] burned up.
Revelation 14:16
And He who sat on the cloud swung His sickle onto the earth, and its crop was harvested.

A noisome

Luke 16:20
And a certain beggar named Lazarus, who was full of sores, was laid at the rich man's doorway.
Acts 12:23
Suddenly, an angel from God struck him [with a terrible condition] because he refused to honor God [by what he said in his speech], so he was consumed by worms and died.

Had

Revelation 13:15
Now the [second] beast was given [the power] to give breath to the statue of the [first] beast, so that it could both speak and cause all those who refused to worship the statue of the [first] beast to be killed.