who shall receive punishment, even eternal perdition, from the presence of the Lord, and from the glory of his power:

Let no man deceive you by any means, for the Lord cometh not, except there come a departing first, and that that sinful man be opened, the son of perdition;

the son of perdition, who opposeth and exalteth himself above all that is called God, or the object of worship; so that he sits as God in the temple of God, shewing himself that he is God.

and by unlimited seduction to evil and with all the deception of wickedness for those who are perishing, because they did not welcome the love of the truth [of the gospel] so as to be saved [they were spiritually blind, and rejected the truth that would have saved them].