'Appointed' in the Bible

and,“A stone of stumbling and a rock of offense”; for they stumble because they disobey the word [of God], and to this they [who reject Him as Savior] were also appointed.

But resist him, be firm in your faith [against his attack—rooted, established, immovable], knowing that the same experiences of suffering are being experienced by your brothers and sisters throughout the world. [You do not suffer alone.]