'Bitterness' in the Bible

So the Spirit lifted me up and took me away, and I went embittered [by the sins of Israel] in the rage of my spirit; and the hand of the Lord was strong on me.

As for you, son of man, groan with breaking heart and bitter grief, groan in their sight.

“And they will make themselves [completely] bald for youAnd wrap themselves in sackcloth;And in bitterness of soul they will weep for youWith bitter mourning and wailing.