'Deeply' in the Bible

Though the king was deeply distressed, because of his oaths and the guests he did not want to refuse her.

Then, looking up to heaven, He sighed deeply and said to him, “Ephphatha!” (that is, “Be opened!”).

But sighing deeply in His spirit, He said, “Why does this generation demand a sign? I assure you: No sign will be given to this generation!”

He took Peter, James, and John with Him, and He began to be deeply distressed and horrified.