'Effect' in the Bible

So Hilkiah, and they whom the king [had commanded], went to Huldah the prophetess, the wife of Shallum the son of Tokhath, the son of Hasrah, keeper of the wardrobe; (now she lived in Jerusalem in the second quarter;) and they spoke to her to that effect.

If you have sinned, what effect do you have against him? If your transgressions are multiplied, what do you do to him?

Yahweh brings the counsel of the nations to nothing. He makes the thoughts of the peoples to be of no effect.

The work of righteousness will be peace; and the effect of righteousness, quietness and confidence forever.

For if those who are of the law are heirs, faith is made void, and the promise is made of no effect.

Now I say this. A covenant confirmed beforehand by God in Christ, the law, which came four hundred thirty years after, does not annul, so as to make the promise of no effect.