'Grief' in the Bible

He was despised and forsaken of men,A man of sorrows and acquainted with grief;And like one from whom men hide their faceHe was despised, and we did not esteem Him.

But the Lord was pleasedTo crush Him, putting Him to grief;If He would render Himself as a guilt offering,He will see His offspring,He will prolong His days,And the good pleasure of the Lord will prosper in His hand.