'Hopeless' in the Bible

Restrain your foot from [being] barefoot, and your throat from thirst. But you said, '[It is] hopeless. No! For I have loved strangers, and after them I will go.'

But they will say, '[It is] hopeless, for we will go after our [own] plans, and each one of us will act [according to] the stubbornness of his evil heart.'