'Itself' in the Bible

because the mind set on the flesh is hostile toward God; for it does not subject itself to the law of God, for it is not even able to do so,

that the creation itself also will be set free from its slavery to corruption into the freedom of the glory of the children of God.

I know and am convinced in the Lord Jesus that nothing is unclean in itself; but to him who thinks anything to be unclean, to him it is unclean.