'Rejected' in the Bible

Anyone who has ignored and set aside the Law of Moses is put to death without mercy on the testimony of two or three witnesses.

For you know that later on, when he wanted [to regain title to] his inheritance of the blessing, he was rejected, for he found no opportunity for repentance [there was no way to repair what he had done, no chance to recall the choice he had made], even though he sought for it with [bitter] tears.