'Trouble' in the Bible

From there I will give back her vineyards to her, and turn the "Valley of Trouble" into an "Opportunity for Hope." There she will sing as she did when she was young, when she came up from the land of Egypt.

I will go back to my place till they are made waste; in their trouble they will go after me early and will make search for me.

May trouble be theirs! for they have gone far away from me; and destruction, for they have been sinning against me; I was ready to be their saviour, but they said false words against me.