'Aching' in the Bible

“My bones are pierced [with aching] in the night season,And the pains that gnaw me take no rest.

"He is being reproved by painful bed rest, with continual aching in his bones.

A glad heart makes a cheerful face; but an aching heart breaks the spirit.

"My anguish, my anguish! I writhe in pain. Oh, the aching of my heart! My heart pounds within me; I cannot keep silent. For I hear the sound of the trumpet, the alarm for war.

"And you, son of man, groan with an aching heart and bitterness; groan before their eyes.