'Disregard' in the Bible

your human infirmity leads me to employ these familiar figures--and just as you once surrendered your faculties into bondage to Impurity and ever-increasing disregard of Law, so you must now surrender them into bondage to Righteousness ever advancing towards perfect holiness.

As it is written and forever remains written, “Jacob I loved (chose, protected, blessed), but Esau I hated (held in disregard compared to Jacob).”