'Frailty' in the Bible

I am speaking in simple terms because of the frailty of your human nature. Just as you once offered the parts of your body as slaves to impurity and to greater and greater disobedience, so now, in the same way, you must offer the parts of your body as slaves to righteousness that leads to sanctification.

For the creation was subjected to frustration and futility, not willingly [because of some intentional fault on its part], but by the will of Him who subjected it, in hope