'Serious' in the Bible

But the Lord punished Pharaoh and his household with severe plagues because of Sarai, Abram’s wife.

The situation distressed Abraham greatly because of his son [Ishmael].

There is a grievous evil which I have seen under the sun: riches being kept and hoarded by their owner to his own misery.

This also is a grievous evil—exactly as he was born, so he shall die. So what advantage has he who labors for the wind?