'Vexation' in the Bible

For in much [human] wisdom there is much displeasure and exasperation; increasing knowledge increases sorrow.

For what does a man get from all his labor and from the striving and sorrow of his heart with which he labors under the sun?

For all his days his work is painful and sorrowful; even at night his mind does not rest. This too is vanity (worthless).

Do not be eager in your heart to be angry,For anger dwells in the heart of fools.

Therefore, remove sorrow and anger from your heart and put away pain from your body, for childhood and the prime of life are fleeting.